"Wolf Tails" is a visual novel where you take care of two wolf-girls. There's Mirari, a kindhearted girl who is running away from her duties to her pack, and Fuyu, a brash and loud-mouthed girl who is wary of human culture and its "influences".
Loved this when I first read it ~6 years ago, still one of my favorite yuris to return to from time to time for a cozy reread. Short and sweet and not especially complicated, but has lots of heart.